ọja

23076-35-9, Xylazine hydrochloride

Apejuwe Kukuru:

Awọn alaye ni kiakia

CAS Bẹẹkọ: 23076-35-9
Awọn orukọ miiran: Xylazine HCl
MF: C12H17ClN2S
EINECS Bẹẹkọ: 245-417-0
Ibi ti Oti: China
Iru: Awọn agbedemeji Oogun
Ti nw: 99%
Orukọ Brand: DUMI
Nọmba awoṣe: 23076-35-9
Ohun elo: Awọn Oogun Eranko
Irisi: Powder Funfun
Iwuwo: 1,15 g / cm3
Iwuwo iṣan: 256.795
Ibi to peye: 256.080109
Logarithmic: 3.51880
Ibi ipamọ: Itura Ati Ibi Gbẹ
Iduroṣinṣin: Idurosinsin Ni Igba otutu otutu Ati Ipa

Ọja Apejuwe

Ibeere

Ọja Tags

Lilo ti Xylazine hydrochloride
Xylazine Hydrochlorideytò: Adrenergic ReceptorXylazine jẹ oogun ti a lo fun sisọ, anesthesia, isinmi iṣan, ati analgesia ninu awọn ẹranko bii awọn ẹṣin, malu ati awọn ẹranko miiran ti kii ṣe eniyan. Afọwọkọ ti clonidine, o jẹ agonist ni kilasi α2 ti olugba adrenergic. Xylazine ti farahan laipe bi oogun iṣere, paapaa ni Puerto Rico [1]. Isakoso ti xylazine (0.17 mg / kg ti iwuwo ara, ti fomi po si iwọn milimita 10, ni lilo 0.9% NaCl) ti o fa to awọn wakati 2.5 ti analgesia agbegbe laisi awọn ipa ẹgbẹ ti o han. Awọn abere ti o ga julọ ti xylazine fa idibajẹ ọwọ ataxia kekere. Isakoso ti lidocaine ṣe idasi akoko kanna ti analgesia, pẹlu ataxia ẹhin ẹsẹ to lagbara (iṣẹlẹ 100%). A pari pe xylazine ti a fun nipasẹ awọn abajade abẹrẹ epidural ni ailewu, analgesia perineal ti o munadoko ninu awọn ẹṣin [2].

Xylazine hydrochloride Iṣẹ iṣe ti Ẹmi

Apejuwe Xylazine Hydrochloride jẹ kilasi α2 ti agonist olugba olugba adrenergic .Ọkọ: Adrenergic Receptor Xylazine jẹ oogun ti a lo fun sisẹ, anesthesia, isinmi iṣan, ati analgesia ninu awọn ẹranko bii ẹṣin, malu ati awọn ẹranko miiran ti kii ṣe eniyan. Afọwọkọ ti clonidine, o jẹ agonist ni kilasi α2 ti olugba adrenergic. Xylazine ti farahan laipe bi oogun iṣere, paapaa ni Puerto Rico [1]. Isakoso ti xylazine (0.17 mg / kg ti iwuwo ara, ti fomi si iwọn 10-milimita, ni lilo 0.9% NaCl) ti o fa to awọn wakati 2.5 ti analgesia agbegbe laisi awọn ipa ẹgbẹ ti o han. Awọn abere ti o ga julọ ti xylazine fa idibajẹ ọwọ ataxia kekere. Isakoso ti lidocaine ṣe idasi akoko kanna ti analgesia, pẹlu ataxia ẹhin ẹsẹ to lagbara (iṣẹlẹ 100%). A pari pe xylazine ti a fun nipasẹ awọn abajade abẹrẹ epidural ni ailewu, analgesia perineal ti o munadoko ninu awọn ẹṣin [2].
Ibatan katalogi
Awọn itọkasi [1]. Reyes, JC, et al., Ijade ti xylazine bi oogun titun ti ilokulo ati awọn abajade ilera rẹ laarin awọn olumulo oogun ni Puerto Rico. J Ilera Ilu, 2012. 89 (3): p. 519-26.[2]. Hsu, WH, ibanujẹ ti o fa Xylazine ati atako rẹ nipasẹ awọn aṣoju idena adrenergic alpha. J Pharmacol Exp Ther, 1981. 218 (1): p. 188-92.

Kemikali & Awọn ohun-ini ti ara

Iwuwo 1.15g / cm3
Oju sise 334.2ºC ni 760mmHg
Ibi yo 150-164? C (dec.)
Agbekalẹ Molikula C12H17ClN2S
Iwuwo molula 256.795
Oju filaṣi 155.9ºC
Mass gangan 256.080109
PSA 49.69000
LogP 3.51880
Ipa Agbara 0,00013mmHg ni 25 ° C
Ipo ifipamọ −20 ° C

Alaye Toxicological

IDANISE EMI

NOMBA RTECS:
XJ0776350
Orukọ Kemikali
4H-1,3-Thiazine, 5,6-dihydro-2- (2,6-xylidino) -, monohydrochloride
NOMBA Iforukọsilẹ CAS:
23076-35-9
TUN TI A TI ṢEYẸ:
199609
Awọn ohun elo DATA TI A TI SỌ:
4
FORMULA MOLEKULA:
C12-H16-N2-S.Cl-H
IWADI MOLEKU:
256,82
ỌLỌRUN ILA ALAYE:
T6N CS AUTJ BMR B1 F1 & GH

DATA IDAJO ILERA

DATA EWU DATA

IRU IDANWO:
TDLo - Iwọn toje ti a tẹjade ti o kere ju
Ọna ti ifihan:
Intramuscular
Awọn iṣẹ ti a ṣe akiyesi:
Eniyan - eniyan
Iwọn lilo / akoko:
14 miligiramu / kg
AWỌN IWỌ NIPA:
Ihuwasi - coma Cardiac - Awọn ayipada EKG kii ṣe iwadii aisan ti awọn ipa ti a ṣalaye Awọn ẹdọfóró, Thorax, tabi Isinmi - awọn ayipada miiran
Itọkasi:
CTOXAO Ile-iwosan Toxicology. (New York, NY) V.1-18, 1968-81. Fun alaye akede, wo JTCTDW. Iwọn didun (ọrọ) / oju-iwe / ọdun: 15,281,1979
IRU IDANWO:
LD50 - Iwọn apaniyan, ida 50 pa
Ọna ti ifihan:
Intramuscular
Awọn iṣẹ ti a ṣe akiyesi:
Rodent - Asin
Iwọn lilo / akoko:
109 mg / kg
AWỌN IWỌ NIPA:
Awọn alaye ti awọn ipa majele ko ṣe iroyin miiran ju iye iwọn lilo apaniyan
Itọkasi:
ZYYZEW Zhongguo Yaolixue Yu Dulixue Zazhi. (Society Pharmacological Society, 27 Tai-Ping Road, Beijing 100850, China) V.1- 1986- Iwọn didun (oro) / oju-iwe / ọdun: 9,96,1995
IRU IDANWO:
LD50 - Iwọn apaniyan, ida 50 pa
Ọna ti ifihan:
Intramuscular
Awọn iṣẹ ti a ṣe akiyesi:
Mammal - aja
Iwọn lilo / akoko:
47 miligiramu / kg
AWỌN IWỌ NIPA:
Awọn alaye ti awọn ipa majele ko ṣe iroyin miiran ju iye iwọn lilo apaniyan
Itọkasi:
CTOXAO Ile-iwosan Toxicology. (New York, NY) V.1-18, 1968-81. Fun alaye akede, wo JTCTDW. Iwọn didun (ọrọ) / oju-iwe / ọdun: 15,281,1979
IRU IDANWO:
LD50 - Iwọn apaniyan, ida 50 pa
Ọna ti ifihan:
Intramuscular
Awọn iṣẹ ti a ṣe akiyesi:
Rodent - Guinea ẹlẹdẹ
Iwọn lilo / akoko:
10 miligiramu / kg
AWỌN IWỌ NIPA:
Awọn alaye ti awọn ipa majele ko ṣe iroyin miiran ju iye iwọn lilo apaniyan
Itọkasi:
VHTODE Veterinary ati Human Toxicology. (American College of Veterinary and Comparative Toxicology, Office Publication, Comparative Toxicology, Manhattan, KS 66506) V.19- 1977- Iwọn didun (oro) / oju-iwe / ọdun: 24,410,1982

Awọn ọrọ kanna

BAY 1470 hydrochloride
Xylazine kiloraidi
2- (2,6-Dimethylphenylamino) -5,6-dihydro-4H-thiazine hydrochloride
2 - [(2,6-Dimethylphenyl) amino] -5,6-dihydro-4H-1, 3-thiazine Hydrochloride
N- (2,6-Dimethylphenyl) -5,6-dihydro-4H-1,3-thiazin-2-amine hydrochloride (1: 1)
BAY VA 1470
EINECS 245-417-0
4H-1,3-Thiazin-2-amine, N- (2, 6-dimethylphenyl) -5,6-dihydro-, hydrochloride (1: 1)
Ayẹyẹ
N- (2,6-Dimethylphenyl) -5, 6-dihydro-4H-1,3-thiazin-2-amine hydrochloride
Xylazine HCl
MFCD00058196

 

 

 

 





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